5 Easy Facts About YAP-TEAD-IN-3 Described
Though ectopic activation of mTORC1 in peripheral tissues is often achieved by administering a substantial dose of exogenous leucine, mTORC1 signaling while in the CNS stays refractory possible because of the speedy turnover and buffering of leucine within the brain18,19. The invention of Sestrin1 and 2 as a specific leucine sensor upstream of mTOR